SubstanceNucleicAcidLinkage constructor

const SubstanceNucleicAcidLinkage({
  1. @JsonKey(name: 'id') String? fhirId,
  2. @JsonKey(name: 'extension') List<FhirExtension>? extension_,
  3. List<FhirExtension>? modifierExtension,
  4. String? connectivity,
  5. @JsonKey(name: '_connectivity') Element? connectivityElement,
  6. Identifier? identifier,
  7. String? name,
  8. @JsonKey(name: '_name') Element? nameElement,
  9. String? residueSite,
  10. @JsonKey(name: '_residueSite') Element? residueSiteElement,
})

SubstanceNucleicAcidLinkage Nucleic acids are defined by three distinct elements: the base, sugar and linkage. Individual substance/moiety IDs will be created for each of these elements. The nucleotide sequence will be always entered in the 5’-3’ direction.

id Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

extension_ ("extension") May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

modifierExtension May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

connectivity The entity that links the sugar residues together should also be captured for nearly all naturally occurring nucleic acid the linkage is a phosphate group. For many synthetic oligonucleotides phosphorothioate linkages are often seen. Linkage connectivity is assumed to be 3’-5’. If the linkage is either 3’-3’ or 5’-5’ this should be specified.

connectivityElement ("_connectivity") Extensions for connectivity

identifier Each linkage will be registered as a fragment and have an ID.

name Each linkage will be registered as a fragment and have at least one name. A single name shall be assigned to each linkage.

nameElement ("_name") Extensions for name

residueSite Residues shall be captured as described in 5.3.6.8.3.

residueSiteElement ("_residueSite") Extensions for residueSite

Implementation

const factory SubstanceNucleicAcidLinkage({
  /// [id] Unique id for the element within a resource (for internal
  ///  references). This may be any string value that does not contain spaces.
  @JsonKey(name: 'id') String? fhirId,

  /// [extension_] ("extension") May be used to represent additional
  ///  information that is not part of the basic definition of the element.
  ///  To make the use of extensions safe and managable, there is a strict
  ///  set of governance applied to the definition and use of extensions.
  ///  Though any implementer can define an extension, there is a set of
  ///  requirements that SHALL be met as part of the definition of the
  ///  extension.
  @JsonKey(name: 'extension') List<FhirExtension>? extension_,

  /// [modifierExtension] May be used to represent additional information
  ///  that is not part of the basic definition of the element and that
  ///  modifies the understanding of the element in which it is contained
  ///  and/or the understanding of the containing element's descendants.
  ///  Usually modifier elements provide negation or qualification. To make
  ///  the use of extensions safe and managable, there is a strict set of
  ///  governance applied to the definition and use of extensions. Though any
  ///  implementer can define an extension, there is a set of requirements
  ///  that SHALL be met as part of the definition of the extension.
  ///  Applications processing a resource are required to check for modifier
  ///  extensions.Modifier extensions SHALL NOT change the meaning of any
  ///  elements on Resource or DomainResource (including cannot change the
  ///  meaning of modifierExtension itself).
  List<FhirExtension>? modifierExtension,

  /// [connectivity] The entity that links the sugar residues together should
  ///  also be captured for nearly all naturally occurring nucleic acid the
  ///  linkage is a phosphate group. For many synthetic oligonucleotides
  ///  phosphorothioate linkages are often seen. Linkage connectivity is
  ///  assumed to be 3’-5’. If the linkage is either 3’-3’ or 5’-5’ this
  ///  should be specified.
  String? connectivity,

  /// [connectivityElement] ("_connectivity") Extensions for connectivity
  @JsonKey(name: '_connectivity') Element? connectivityElement,

  /// [identifier] Each linkage will be registered as a fragment and have an
  ///  ID.
  Identifier? identifier,

  /// [name] Each linkage will be registered as a fragment and have at least
  ///  one name. A single name shall be assigned to each linkage.
  String? name,

  /// [nameElement] ("_name") Extensions for name
  @JsonKey(name: '_name') Element? nameElement,

  /// [residueSite] Residues shall be captured as described in 5.3.6.8.3.
  String? residueSite,

  /// [residueSiteElement] ("_residueSite") Extensions for residueSite
  @JsonKey(name: '_residueSite') Element? residueSiteElement,
}) = _SubstanceNucleicAcidLinkage;