MolecularSequenceVariant constructor
- @JsonKey(name: 'id') FhirId? fhirId,
- @JsonKey(name: 'extension') List<
FhirExtension> ? extension_, - List<
FhirExtension> ? modifierExtension, - FhirInteger? start,
- @JsonKey(name: '_start') Element? startElement,
- FhirInteger? end,
- @JsonKey(name: '_end') Element? endElement,
- String? observedAllele,
- @JsonKey(name: '_observedAllele') Element? observedAlleleElement,
- String? referenceAllele,
- @JsonKey(name: '_referenceAllele') Element? referenceAlleleElement,
- String? cigar,
- @JsonKey(name: '_cigar') Element? cigarElement,
- Reference? variantPointer,
MolecularSequenceVariant Raw data describing a biological sequence.
id Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
extension_
May be used to represent additional information that is not
part of the basic definition of the element. To make the use of extensions
safe and manageable, there is a strict set of governance applied to the
definition and use of extensions. Though any implementer can define an
extension, there is a set of requirements that SHALL be met as part of the
definition of the extension.
modifierExtension
May be used to represent additional information that
is not part of the basic definition of the element and that modifies the
understanding of the element in which it is contained and/or the
understanding of the containing element's descendants. Usually modifier
elements provide negation or qualification. To make the use of extensions
safe and manageable, there is a strict set of governance applied to the
definition and use of extensions. Though any implementer can define an
extension, there is a set of requirements that SHALL be met as part of the
definition of the extension. Applications processing a resource are
required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on
Resource or DomainResource (including cannot change the meaning of
modifierExtension itself).
start
Start position of the variant on the reference sequence. If the
coordinate system is either 0-based or 1-based, then start position is
inclusive.
startElement
Extensions for start
end
End position of the variant on the reference sequence. If the
coordinate system is 0-based then end is exclusive and does not include
the last position. If the coordinate system is 1-base, then end is
inclusive and includes the last position.
endElement
Extensions for end
observedAllele
An allele is one of a set of coexisting sequence
variants of a gene
(SO:0001023).
Nucleotide(s)/amino acids from start position of sequence to stop position
of sequence on the positive (+) strand of the observed sequence. When the
sequence type is DNA, it should be the sequence on the positive (+)
strand. This will lay in the range between variant.start and variant.end.
observedAlleleElement
Extensions for observedAllele
referenceAllele
An allele is one of a set of coexisting sequence
variants of a gene
(SO:0001023).
Nucleotide(s)/amino acids from start position of sequence to stop position
of sequence on the positive (+) strand of the reference sequence. When the
sequence type is DNA, it should be the sequence on the positive (+)
strand. This will lay in the range between variant.start and variant.end.
referenceAlleleElement
Extensions for referenceAllele
cigar
Extended CIGAR string for aligning the sequence with reference
bases. See detailed documentation
(http://support.illumina.com/help/SequencingAnalysisWorkflow/Content/Vault/Informatics/Sequencing_Analysis/CASAVA/swSEQ_mCA_ExtendedCIGARFormat.htm).
cigarElement
Extensions for cigar
variantPointer
A pointer to an Observation containing variant
information.
Implementation
const factory MolecularSequenceVariant({
/// [id] Unique id for the element within a resource (for internal
/// references). This may be any string value that does not contain spaces.
@JsonKey(name: 'id') FhirId? fhirId,
/// [extension_] May be used to represent additional information that is not
/// part of the basic definition of the element. To make the use of extensions
/// safe and manageable, there is a strict set of governance applied to the
/// definition and use of extensions. Though any implementer can define an
/// extension, there is a set of requirements that SHALL be met as part of the
/// definition of the extension.
@JsonKey(name: 'extension') List<FhirExtension>? extension_,
/// [modifierExtension] May be used to represent additional information that
/// is not part of the basic definition of the element and that modifies the
/// understanding of the element in which it is contained and/or the
/// understanding of the containing element's descendants. Usually modifier
/// elements provide negation or qualification. To make the use of extensions
/// safe and manageable, there is a strict set of governance applied to the
/// definition and use of extensions. Though any implementer can define an
/// extension, there is a set of requirements that SHALL be met as part of the
/// definition of the extension. Applications processing a resource are
/// required to check for modifier extensions.
/// Modifier extensions SHALL NOT change the meaning of any elements on
/// Resource or DomainResource (including cannot change the meaning of
/// modifierExtension itself).
List<FhirExtension>? modifierExtension,
/// [start] Start position of the variant on the reference sequence. If the
/// coordinate system is either 0-based or 1-based, then start position is
/// inclusive.
FhirInteger? start,
/// [startElement] Extensions for start
@JsonKey(name: '_start') Element? startElement,
/// [end] End position of the variant on the reference sequence. If the
/// coordinate system is 0-based then end is exclusive and does not include
/// the last position. If the coordinate system is 1-base, then end is
/// inclusive and includes the last position.
FhirInteger? end,
/// [endElement] Extensions for end
@JsonKey(name: '_end') Element? endElement,
/// [observedAllele] An allele is one of a set of coexisting sequence
/// variants of a gene
/// ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)).
/// Nucleotide(s)/amino acids from start position of sequence to stop position
/// of sequence on the positive (+) strand of the observed sequence. When the
/// sequence type is DNA, it should be the sequence on the positive (+)
/// strand. This will lay in the range between variant.start and variant.end.
String? observedAllele,
/// [observedAlleleElement] Extensions for observedAllele
@JsonKey(name: '_observedAllele') Element? observedAlleleElement,
/// [referenceAllele] An allele is one of a set of coexisting sequence
/// variants of a gene
/// ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)).
/// Nucleotide(s)/amino acids from start position of sequence to stop position
/// of sequence on the positive (+) strand of the reference sequence. When the
/// sequence type is DNA, it should be the sequence on the positive (+)
/// strand. This will lay in the range between variant.start and variant.end.
String? referenceAllele,
/// [referenceAlleleElement] Extensions for referenceAllele
@JsonKey(name: '_referenceAllele') Element? referenceAlleleElement,
/// [cigar] Extended CIGAR string for aligning the sequence with reference
/// bases. See detailed documentation
/// (http://support.illumina.com/help/SequencingAnalysisWorkflow/Content/Vault/Informatics/Sequencing_Analysis/CASAVA/swSEQ_mCA_ExtendedCIGARFormat.htm).
String? cigar,
/// [cigarElement] Extensions for cigar
@JsonKey(name: '_cigar') Element? cigarElement,
/// [variantPointer] A pointer to an Observation containing variant
/// information.
Reference? variantPointer,
}) = _MolecularSequenceVariant;